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March 15, 2006

Potential herbal formula solution for peanut allergy

source: Reuters Health

Treatment of peanut allergic mice with the Chinese herbal formula known as FAHF-2 completely blocks peanut-induced allergic reactions for up to 6 months following therapy and full protection is restored following a second course of FAHF-2, investigators report.

These observations, if reproducible in humans, suggest that this Chinese herbal formula may be a highly effective treatment for peanut allergy, study investigators say. The findings were presented Tuesday in Miami at the American Academy of Allergy, Asthma and Immunology's annual meeting.

Following treatment with FAHF-2 for 7 weeks, peanut-allergic mice were completely protected against peanut-induced reactions following oral challenges administered up to 34 weeks after treatment, lead investigator Dr. Kamal D. Srivastava from Mount Sinai School of Medicine in New York reported.

Subsequent challenges at week 40 and 50 showed "only modest declines" in protection, the team reports, with 1 in 10 mice reacting to peanut challenge at week 40 and 3 in 10 at week 50.

Full protection was restored with re-treatment with FAHF-2; no mouse reacted to oral peanut challenge administered at week 66.

"This is a significant finding in terms of the duration of protection with a single course of treatment that can be taken orally, making it an effective and convenient treatment that can be administered at home," Srivastava told Reuters Health.


Posted by David at March 15, 2006 11:41 AM